Project description

Highly motivated candidates interested in structural studies of disease-related signaling complexes (MAPK and mTOR) are invited to apply for a fully funded PhD position in the laboratory of Dr. Andreas Naschberger in the Biological and Environmental Sciences and Engineering (BESE) Division at the King Abdullah University of Science and Technology (KAUST).

The position suits recent Master’s graduates, with a career interest in structural biology. We are using cryo-EM and other biochemical/biophysical methods to characterize disease-related protein assemblies involved in cell signaling. The lab offers an excellent equipped environment where experimental lab work in protein purification is channeled into structural studies using cryo-EM. We ask fundamental questions about how human signaling protein complexes function within their regulatory networks. The project specifically targets the regulation and dynamics of these complexes at near-atomic resolution.

Selection criteria

Master’s degree in a relevant discipline area, such as Molecular Biology, Biotechnology, Biochemistry, Structural Biology, or Bioengineering

Experience in protein purification from E.coli, insect and mammalian cell culture

Experience in the cryo-EM workflow (data collection, data processing, and model building) would be considered as plus

Creative and self-motivated personality with an interest in fundamental and applied science

A record of publications in quality, peer-reviewed journals is not necessary but would be considered as plus

Excellent problem-solving skills

Good interpersonal skills

Excellent communication skills in English

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